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- Title
Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus.
- Authors
Morales, Gracia; Picazo, Juan J; Baos, Elvira; Candel, Francisco J; Arribi, Ana; Peláez, Beatriz; Andrade, Raquel; de la Torre, María-Angeles; Fereres, José; Sánchez-García, Miguel
- Abstract
From April through June 2008, we identified 12 patients in the intensive care unit and 3 patients on other wards infected with methicillin-resistant Staphylococcus aureus that was also resistant to linezolid. We investigated the mechanism of resistance--point mutations in domain V of 23S ribosomal RNA (rRNA) or presence of the cfr gene--involved in the outbreak.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Vol 50, Issue 6, p821
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/650574