We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Switch from enfuvirtide to raltegravir in virologically suppressed multidrug-resistant HIV-1-infected patients: a randomized open-label trial.
- Authors
De Castro, Nathalie; Braun, Joséphine; Charreau, Isabelle; Pialoux, Gilles; Cotte, Laurent; Katlama, Christine; Raffi, François; Weiss, Laurence; Meynard, Jean-Luc; Yazdanpanah, Yazdan; Delaugerre, Constance; Madelaine-Chambrin, Isabelle; Aboulker, Jean-Pierre; Molina, Jean-Michel; EASIER ANRS 138 study group
- Abstract
Among patients with multidrug-resistant human immunodeficiency virus type 1 (HIV-1) infection, salvage regimens including enfuvirtide have demonstrated sustained efficacy. Because of reluctance to use subcutaneous injections, raltegravir may be an alternative to replace enfuvirtide within a suppressive regimen. We conducted a prospective, randomized, open-label trial to compare the antiviral efficacy and safety of a switch to raltegravir with the efficacy and safety of continuing enfuvirtide.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Vol 49, Issue 8, p1259
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/605674