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Title
Epidemiological evidence for serotype-independent acquired immunity to pneumococcal carriage.
Authors
Granat, Simo M; Ollgren, Jukka; Herva, Elja; Mia, Zakaria; Auranen, Kari; Mäkelä, P Helena
Abstract
Asymptomatic nasopharyngeal carriage is the main reservoir for transmission of Streptococcus pneumoniae. The rate of both carriage and pneumococcal disease decreases with age. To what extent these changes are the result of developing natural immunity is currently a subject of debate.
Publication
The Journal of infectious diseases, 2009, Vol 200, Issue 1, p99