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- Title
The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier.
- Authors
van Sorge, Nina M; Quach, Darin; Gurney, Michael A; Sullam, Paul M; Nizet, Victor; Doran, Kelly S
- Abstract
Group B Streptococcus (GBS) is the leading cause of bacterial meningitis in newborn infants. Because GBS is able to invade, survive, and cross the blood-brain barrier, we sought to identify surface-expressed virulence factors that contribute to blood-brain barrier penetration and the pathogenesis of meningitis.
- Publication
The Journal of infectious diseases, 2009, Vol 199, Issue 10, p1479
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/598217