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- Title
Vaccines and autism: a tale of shifting hypotheses.
- Authors
Gerber, Jeffrey S; Offit, Paul A
- Abstract
Although child vaccination rates remain high, some parental concern persists that vaccines might cause autism. Three specific hypotheses have been proposed: (1) the combination measles-mumps-rubella vaccine causes autism by damaging the intestinal lining, which allows the entrance of encephalopathic proteins; (2) thimerosal, an ethylmercury-containing preservative in some vaccines, is toxic to the central nervous system; and (3) the simultaneous administration of multiple vaccines overwhelms or weakens the immune system. We will discuss the genesis of each of these theories and review the relevant epidemiological evidence.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Vol 48, Issue 4, p456
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/596476