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- Title
Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox.
- Authors
Paran, Nir; Suezer, Yasemin; Lustig, Shlomo; Israely, Tomer; Schwantes, Astrid; Melamed, Sharon; Katz, Lior; Preuss, Thomas; Hanschmann, Kay-Martin; Kalinke, Ulrich; Erez, Noam; Levin, Reuven; Velan, Baruch; Löwer, Johannes; Shafferman, Avigdor; Sutter, Gerd
- Abstract
Decades after the cessation of smallpox vaccination, the potential of the deliberate release of pathogenic orthopoxviruses has forced a reconsideration of using these extremely efficient human vaccines. Scenarios of sudden biothreats have prompted demand for rapidly protective vaccination. However, the feasibility of short-term vaccination (i.e., vaccination shortly before exposure) with vaccinia virus (VACV) is uncertain.
- Publication
The Journal of infectious diseases, 2009, Vol 199, Issue 1, p39
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/595565