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- Title
Effect of Borrelia burgdorferi genotype on the sensitivity of C6 and 2-tier testing in North American patients with culture-confirmed Lyme disease.
- Authors
Wormser, Gary P; Liveris, Dionysios; Hanincová, Klára; Brisson, Dustin; Ludin, Sara; Stracuzzi, Vincent J; Embers, Monica E; Philipp, Mario T; Levin, Andrew; Aguero-Rosenfeld, Maria; Schwartz, Ira
- Abstract
A potential concern with any serologic test to detect antibodies to Borrelia burgdorferi is whether the epitopes incorporated in the test provide sufficient cross-reactivity to detect infection with all of the pathogenic strains of the species. This is a particular concern for the C6 test, which is based on reactivity to a single peptide.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Vol 47, Issue 7, p910
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/591529