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- Title
CD4<sup>+</sup> T Cell Depletion in an Untreated HIV Type 1-Infected Human Leukocyte Antigen-B*5801-Positive Patient with an Undetectable Viral Load.
- Authors
Andrade, Adriana; Bailey, Justin R.; Jie Xu; Philp, Frances H.; Quinn, Thomas C.; Williams, Thomas M.; Ray, Stuart C.; Thomas, David L.; Blankson, Joel N.
- Abstract
We report a case of a patient infected with human immunodeficiency virus type 1 (HIV-1) for 20 years who has experienced CD4+ T cell depletion in spite of maintaining undetectable viral loads. Our data suggest that immune activation can cause CD4+ T cell depletion even when HIV-1 replication appears to be controlled by host factors.
- Publication
Clinical Infectious Diseases, 2008, Vol 46, Issue 8, pe78
- ISSN
1058-4838
- Publication type
Academic Journal
- DOI
10.1086/529387