We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes.
- Authors
Pascual, Andres; Calandra, Thierry; Bolay, Saskia; Buclin, Thierry; Bille, Jacques; Marchetti, Oscar
- Abstract
Voriconazole is the therapy of choice for aspergillosis and a new treatment option for candidiasis. Liver disease, age, genetic polymorphism of the cytochrome CYP2C19, and comedications influence voriconazole metabolism. Large variations in voriconazole pharmacokinetics may be associated with decreased efficacy or with toxicity.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Vol 46, Issue 2, p201
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/524669