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- Title
Lack of association between group B meningococcal disease and autoimmune disease.
- Authors
Howitz, Michael; Krause, Tyra Grove; Simonsen, Jacob Brunbjerg; Hoffmann, Steen; Frisch, Morten; Nielsen, Nete Munk; Robbins, John; Schneerson, Rachel; Mølbak, Kåre; Miller, Mark A
- Abstract
The capsular polysaccharide of group B meningococci (GBM) is structurally identical to a polysaccharide found on neural cell adhesion molecules in humans. This structural identity has raised concern that a vaccine based on the GBM capsular polysaccharide might induce autoimmune disease in vaccinated persons. Because systemic infection with GBM induces serum antibody in adults, we investigated whether persons with a history of GBM disease are at increased risk of developing autoimmune diseases.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Vol 45, Issue 10, p1327
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/522190