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- Title
Potential risks and benefits of HIV treatment simplification: a simulation model of a proposed clinical trial.
- Authors
Schackman, Bruce R; Scott, Callie A; Sax, Paul E; Losina, Elena; Wilkin, Timothy J; McKinnon, John E; Swindells, Susan; Weinstein, Milton C; Freedberg, Kenneth A
- Abstract
In recent studies, subjects who had achieved suppression of the human immunodeficiency virus (HIV) RNA level while receiving an initial 3-drug antiretroviral regimen successfully maintained suppression while receiving treatment with a "boosted" protease inhibitor (PI) alone. We projected the long-term outcomes of this treatment simplification strategy to inform the design of a proposed multicenter, randomized clinical trial.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Vol 45, Issue 8, p1062
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/521933