We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.
- Authors
Zar, Fred A; Bakkanagari, Srinivasa R; Moorthi, K M L S T; Davis, Melinda B
- Abstract
The incidence and severity of Clostridium difficile-associated diarrhea (CDAD) has been increasing, and there have been recent reports of metronidazole treatment failure. Metronidazole is still commonly used as first-line treatment for CDAD but has never been compared with vancomycin in a prospective, randomized, double-blind, placebo-controlled trial. We conducted such a trial, stratifying patients according to disease severity, to investigate whether one agent was superior for treating either mild or severe disease.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Vol 45, Issue 3, p302
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/519265