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- Title
Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study.
- Authors
Parienti, Jean-Jacques; Massari, Veronique; Rey, David; Poubeau, Patrice; Verdon, Renaud; SIROCCO study team
- Abstract
Many antiretroviral therapies, including efavirenz, are associated with increased serum concentrations of low-density lipoprotein cholesterol. In a small 52-week randomized study, we found that switching from efavirenz to nevirapine was associated with significantly decreased low-density lipoprotein cholesterol levels, compared with continuation of efavirenz therapy (P<.04). A switch to nevirapine was associated with no severe adverse events.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Vol 45, Issue 2, p263
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/518973