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- Title
Serogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization.
- Authors
Snape, Matthew D; Kelly, Dominic F; Salt, Penny; Green, Sarah; Snowden, Claire; Diggle, Linda; Borkowski, Astrid; Yu, Ly-mee; Moxon, E Richard; Pollard, Andrew J
- Abstract
The persistence of protection from meningococcal disease following immunization with serogroup C meningococcal (MenC) glycoconjugate vaccines in infancy is short-lived. The duration of protective immunity afforded by these vaccines in other at-risk age groups (i.e., adolescents and young adults) is not known. We evaluated the persistence of bactericidal antibodies following immunization with a MenC glycoconjugate vaccine (MenCV) in adolescents and the kinetics of immune response to a meningococcal AC plain polysaccharide vaccine (MenPS) challenge or a repeat dose of MenCV.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Vol 43, Issue 11, p1387
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/508776