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- Title
MassTag polymerase-chain-reaction detection of respiratory pathogens, including a new rhinovirus genotype, that caused influenza-like illness in New York State during 2004-2005.
- Authors
Lamson, Daryl; Renwick, Neil; Kapoor, Vishal; Liu, Zhiqiang; Palacios, Gustavo; Ju, Jingyue; Dean, Amy; St George, Kirsten; Briese, Thomas; Lipkin, W Ian
- Abstract
In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management.
- Publication
The Journal of infectious diseases, 2006, Vol 194, Issue 10, p1398
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/508551