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- Title
A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.
- Authors
Hecht, Frederick M; Wang, Lei; Collier, Ann; Little, Susan; Markowitz, Martin; Margolick, Joseph; Kilby, J Michael; Daar, Eric; Conway, Brian; Holte, Sarah; AIEDRP Network
- Abstract
Uncontrolled studies have suggested a benefit, after treatment discontinuation, of initiating highly active antiretroviral therapy (HAART) during primary human immunodeficiency virus (HIV) infection. We assessed whether initiation of HAART within 2 weeks of (acute treatment) or between 2 weeks and 6 months after (early treatment) HIV seroconversion was associated with improvements in the viral load and the CD4+ T cell count after discontinuation of treatment in an observational cohort.
- Publication
The Journal of infectious diseases, 2006, Vol 194, Issue 6, p725
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/506616