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- Title
Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine.
- Authors
Rock, Michael T; Yoder, Sandra M; Talbot, Thomas R; Edwards, Kathryn M; Crowe, James E, Jr
- Abstract
Recent primary vaccine trials of diluted Aventis Pasteur smallpox vaccine (APSV) demonstrated that immunization "take" rates, defined by the presence of a vesicle or pustule ("take") at the inoculation site 6-11 days after immunization, did not differ between the dilution groups. To our knowledge, there have been no studies that examine the cellular immune response or that distinguish CD4(+) T cell responses from CD8(+) T cell responses after primary immunization with varying dilutions of APSV.
- Publication
The Journal of infectious diseases, 2006, Vol 194, Issue 4, p435
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/505506