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- Title
Plasma nevirapine levels and 24-week efficacy in HIV-infected patients receiving nevirapine-based highly active antiretroviral therapy with or without rifampicin.
- Authors
Manosuthi, Weerawat; Sungkanuparph, Somnuek; Thakkinstian, Ammarin; Rattanasiri, Sasivimol; Chaovavanich, Achara; Prasithsirikul, Wisit; Likanonsakul, Sirirat; Ruxrungtham, Kiat
- Abstract
Seventy human immunodeficiency virus (HIV)-infected patients receiving rifampicin and 70 HIV-infected patients not receiving rifampicin were enrolled to receive 400 mg of nevirapine-based highly active antiretroviral therapy per day. Mean plasma nevirapine levels at 8 and 12 weeks were lower in patients receiving rifampicin (P=.048). However, virological and immunological outcomes at 24 weeks were not different between the 2 groups (P>.05).
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Vol 43, Issue 2, p253
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/505210