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- Title
Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment.
- Authors
Gallant, Joel E; Parish, Michelle A; Keruly, Jeanne C; Moore, Richard D
- Abstract
In our large observational cohort, use of tenofovir disoproxil fumarate (n=344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n=314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Vol 40, Issue 8, p1194
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/428840