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- Title
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes.
- Authors
Francis, John S; Doherty, Meg C; Lopatin, Uri; Johnston, Cecilia P; Sinha, Gita; Ross, Tracy; Cai, Mian; Hansel, Nadia N; Perl, Trish; Ticehurst, John R; Carroll, Karen; Thomas, David L; Nuermberger, Eric; Bartlett, John G
- Abstract
Recent worldwide reports of community-onset skin abscesses, outbreaks of furunculosis, and severe pneumonia associated with methicillin-resistant Staphylococcus aureus (MRSA) carrying Panton-Valentine leukocidin (PVL) genes and the staphylococcal cassette chromosome mec (SCCmec) type IV indicate that MRSA infections are evolving into a community-related problem. The majority of cases reported to date involve skin and soft-tissue infections, with severe pneumonia representing a relatively rare phenomenon. During a 2-month period in the winter of 2003-2004, four healthy adults presented to 1 of 2 Baltimore hospitals with severe necrotizing MRSA pneumonia in the absence of typical risk factors for MRSA infection.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Vol 40, Issue 1, p100
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/427148