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- Title
Mass antibiotic treatment and community protection in trachoma control programs.
- Authors
Chidambaram, Jaya D; Melese, Muluken; Alemayehu, Wondu; Yi, Elizabeth; Prabriputaloong, Tisha; Lee, David C; Cevallos, Vicky; Zhou, Zhaoxia; Whitcher, John P; Gaynor, Bruce D; Lietman, Thomas M
- Abstract
Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., "herd protection") that has been observed in vaccination programs are discussed.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Vol 39, Issue 9, pe95
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/424747