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- Title
Fosmidomycin-clindamycin for Plasmodium falciparum Infections in African children.
- Authors
Borrmann, Steffen; Adegnika, Ayola A; Matsiegui, Pierre-Blaise; Issifou, Saadou; Schindler, Andreas; Mawili-Mboumba, Denise P; Baranek, Thomas; Wiesner, Jochen; Jomaa, Hassan; Kremsner, Peter G
- Abstract
Fosmidomycin is a new antimalarial drug with a novel mechanism of action. Studies in Africa that have evaluated fosmidomycin as monotherapeutic agent demonstrated its excellent tolerance, but 3-times-daily treatment regimens of >or=4 days were required to achieve radical cure, prompting further research to identify and validate a suitable combination partner to enhance its efficacy.
- Publication
The Journal of infectious diseases, 2004, Vol 189, Issue 5, p901
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/381785