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- Title
Epidemiology of human papillomavirus infection and abnormal cytologic test results in an urban adolescent population.
- Authors
Tarkowski, Trudee A; Koumans, Emilia H; Sawyer, Mary; Pierce, Antonya; Black, Carolyn M; Papp, John R; Markowitz, Lauri; Unger, Elizabeth R
- Abstract
We determined the prevalence of and the risk factors for human papillomavirus (HPV) infection and abnormal cytologic test results in 312 adolescent girls (mean age, 16.1 years). Subjects had a median of 2 years of sexual activity and 4 lifetime sex partners. Cervical HPV was detected by use of L1-consensus polymerase chain reaction in 64% of subjects; half of those with HPV had >1 type, and 77% had >/=1 high-risk type. Independent risk factors for HPV were lifetime number of sex partners, age of partner, and douching. Cytologic abnormalities were common (20.9% of subjects had atypical squamous cells of uncertain significance, and 17.0% had high- or low-grade squamous intraepithelial lesions) and were significantly associated with detection of HPV (P=.0001); however, most (51.6%) subjects with HPV had normal cytologic test results.
- Publication
The Journal of infectious diseases, 2004, Vol 189, Issue 1, p46
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/380466