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- Title
Etiological diagnosis of childhood pneumonia by use of transthoracic needle aspiration and modern microbiological methods.
- Authors
Vuori-Holopainen, Elina; Salo, Eeva; Saxén, Harri; Hedman, Klaus; Hyypiä, Timo; Lahdenperä, Raija; Leinonen, Maija; Tarkka, Eveliina; Vaara, Martti; Peltola, Heikki
- Abstract
Childhood pneumonia is usually treated without determining its etiology. The causative organism can be isolated from specimens of blood, empyema fluid, or lung aspirate, but this is rarely done. The potential of transthoracic needle aspiration for identification of causative agents was tested with use of modern microbiological methods. Aspiration was performed for 34 children who had radiological signs compatible with community-acquired pneumonia and had alveolar consolidation. In addition to bacterial and viral cultures and viral antigen detection, nucleic acid detection for common respiratory pathogens was performed on aspirate specimens. Aspiration disclosed the etiology in 20 (59%) of 34 cases overall and in 18 (69%) of 26 patients from whom a representative specimen was obtained. Aspiration's advantages are high microbiological yield and a relatively low risk of a clinically significant adverse event. Aspiration should be used if identification of the causative agent outweighs the modest risk of the procedure.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Vol 34, Issue 5, p583
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1086/338642