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- Title
Penetration of the nucleoside analogue abacavir into the genital tract of men infected with human immunodeficiency virus type 1.
- Authors
van Praag, R M; van Heeswijk, R P; Jurriaans, S; Lange, J M; Hoetelmans, R M; Prins, J M
- Abstract
The male genital tract is considered an anatomical reservoir during therapy for human immunodeficiency virus infection, because the blood-testis barrier may prevent antiretroviral drugs (e.g., the protease inhibitors ritonavir, saquinavir and nelfinavir) from entering the male genital tract. To our knowledge, there are currently no available data on the penetration of the nucleoside analogue abacavir into the male genital tract. Our report shows that abacavir has good penetration into the male genital tract.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Vol 33, Issue 8, pe91
- ISSN
1058-4838
- Publication type
Journal Article
- DOI
10.1086/322682