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- Title
Outbreak of human parainfluenza virus 3 infections in a hematopoietic stem cell transplant population.
- Authors
Cortez, K J; Erdman, D D; Peret, T C; Gill, V J; Childs, R; Barrett, A J; Bennett, J E
- Abstract
Clinical manifestations and epidemiological features are described for a cluster of 12 cases of human parainfluenza virus 3 (HPIV3) infection that occurred among 64 allogeneic hematopoietic stem cell transplant (SCT) recipients in an 11-week period during spring 2000. Upper respiratory symptoms predominated. Pneumonia occurred in 3 patients and was a contributing factor in the death of 1 patient. Exposure histories and molecular analysis of HPIV3 isolates suggested that both community acquired and nosocomially transmitted infections occurred during this outbreak. A chain of transmission within the outpatient clinic appeared to have occurred in 4 outpatients and to have extended to 2 hospitalized patients. Molecular epidemiology was useful in discerning routes of transmission in this outbreak.
- Publication
The Journal of infectious diseases, 2001, Vol 184, Issue 9, p1093
- ISSN
0022-1899
- Publication type
Journal Article
- DOI
10.1086/322041