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- Title
Treatment of latent tuberculosis infection in patients aged > or =35 years.
- Authors
Gilroy, S A; Rogers, M A; Blair, D C
- Abstract
Treating patients aged > or =35 years for tuberculosis infection has been controversial because of the hepatotoxic effects of isoniazid. A 2-year retrospective cohort study of outpatient medical records determined the completion rate in this age group and identified risk factors associated with isoniazid-associated hepatotoxicity. Isoniazid preventative therapy was well tolerated. However, toxicity occurred in women receiving concomitant medications and men who used alcohol.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Vol 31, Issue 3, p826
- ISSN
1058-4838
- Publication type
Journal Article
- DOI
10.1086/314037