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- Title
Acute lung injury in leptospirosis: clinical and laboratory features, outcome, and factors associated with mortality.
- Authors
Marotto, P C; Nascimento, C M; Eluf-Neto, J; Marotto, M S; Andrade, L; Sztajnbok, J; Seguro, A C
- Abstract
Forty-two consecutive patients with leptospirosis and acute lung injury who were mechanically ventilated were analyzed in a prospective cohort study. Nineteen patients (45%) survived, and 23 (55%) died. Multivariate analysis revealed that 3 variables were independently associated with mortality: hemodynamic disturbance (odds ratio [OR], 6.0; 95% confidence interval [CI], 0.9-38.8; P=. 047), serum creatinine level >265.2 micromol/L (OR, 10.6; 95% CI, 0. 9-123.7; P =.026), and serum potassium level >4.0 mmol/L (OR, 19.9; 95% CI, 1.2-342.8; P=.009). These observations can be used to identify factors associated with mortality early in the course of severe respiratory failure in leptospirosis.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Vol 29, Issue 6, p1561
- ISSN
1058-4838
- Publication type
Journal Article
- DOI
10.1086/313501