Works matching AU Jim C. Norman

Results: 38

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

Published in:

Nature Medicine, 2009, v. 15, n. 4, p. 392, doi. 10.1038/nm.1941

By:

Reynolds, Andrew R.;
Hart, Ian R.;
Watson, Alan R.;
Welti, Jonathan C.;
Silva, Rita G.;
Robinson, Stephen D.;
Da Violante, Georges;
Gourlaouen, Morgane;
Salih, Mishal;
Jones, Matt C.;
Jones, Dylan T.;
Saunders, Garry;
Kostourou, Vassiliki;
Perron-Sierra, Françoise;
Norman, Jim C.;
Tucker, Gordon C.;
Hodivala-Dilke, Kairbaan M.

Publication type:

Article

RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 6, p. 917, doi. 10.1083/jcb.201302041

By:

Jacquemet, Guillaume;
Green, David M.;
Bridgewater, Rebecca E.;
Von Kriegsheim, Alexander;
Humphries, Martin J.;
Norman, Jim C.;
Caswell, Patrick T.

Publication type:

Article

N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.

Published in:

Journal of Cell Biology, 2012, v. 199, n. 3, p. 527, doi. 10.1083/jcb.201203025

By:

Xinzi Yu;
Zech, Tobias;
McDonald, Laura;
Gonzalez, Esther Garcia;
Ang Li;
Macpherson, Iain;
Schwarz, Juliane P.;
Spence, Heather;
Futó, Kinga;
Timpson, Paul;
Nixon, Colin;
Yafeng Ma;
Anton, Ines M.;
Visegrády, Balázs;
Insall, Robert H.;
Oien, Karin;
Blyth, Karen;
Norman, Jim C.;
Machesky, Laura M.

Publication type:

Article

Rab5c promotes AMAP1--PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.

Published in:

Journal of Cell Biology, 2012, v. 197, n. 7, p. 983, doi. 10.1083/jcb.201201065

By:

Onodera, Yasuhito;
Jin-Min Nam;
Ari Hashimoto;
Norman, Jim C.;
Shirato, Hiroki;
Hashimoto, Shigeru;
Hisataka Sabe

Publication type:

Article

Diacylglycerol kinase α controls RCP-dependent integrin traficking to promote invasive migration.

Published in:

Journal of Cell Biology, 2012, v. 196, n. 2, p. 277, doi. 10.1083/jcb.201109112

By:

Rainero, Elena;
Caswell, Patrick T.;
Muller, Patricia A. J.;
Grindlay, Joan;
McCaffrey, Mary W.;
Zhang, Qifeng;
Wakelam, Michael J. O.;
Vousden, Karen H.;
Graziani, Andrea;
Norman, Jim C.

Publication type:

Article

p53 and its mutants in tumor cell migration and invasion.

Published in:

Journal of Cell Biology, 2011, v. 192, n. 2, p. 209, doi. 10.1083/jcb.201009059

By:

Muller, Patricia A. J.;
Vousden, Karen H.;
Norman, Jim C.

Publication type:

Article

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

Published in:

Journal of Cell Biology, 2008, v. 183, n. 1, p. 143, doi. 10.1083/jcb.200804140

By:

Caswell, Patrick T.;
Chan, May;
Lindsay, Andrew J.;
McCaffrey, Mary W.;
Boettiger, David;
Norman, Jim C.

Publication type:

Article

αvβ3 and α5β1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration.

Published in:

Journal of Cell Biology, 2007, v. 177, n. 3, p. 515, doi. 10.1083/jcb.200609004

By:

White, Dominic P.;
Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.63807

By:

Nászai, Máté;
Bellec, Karen;
Yachuan Yu;
Román-Fernández, Alvaro;
Sandilands, Emma;
Johansson, Joel;
Campbell, Andrew D.;
Norman, Jim C.;
Sansom, Owen J.;
Bryant, David M.;
Cordero, Julia B.

Publication type:

Article

Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26839-y

By:

Marco, Sergi;
Neilson, Matthew;
Moore, Madeleine;
Perez-Garcia, Arantxa;
Hall, Holly;
Mitchell, Louise;
Lilla, Sergio;
Blanco, Giovani R.;
Hedley, Ann;
Zanivan, Sara;
Norman, Jim C.

Publication type:

Article

The Diacylglycerol Kinase α/Atypical PKC/β1 Integrin Pathway in SDF-1α Mammary Carcinoma Invasiveness.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0097144

By:

Rainero, Elena;
Cianflone, Cristina;
Porporato, Paolo Ettore;
Chianale, Federica;
Malacarne, Valeria;
Bettio, Valentina;
Ruffo, Elisa;
Ferrara, Michele;
Benecchia, Fabio;
Capello, Daniela;
Paster, Wolfgang;
Locatelli, Irene;
Bertoni, Alessandra;
Filigheddu, Nicoletta;
Sinigaglia, Fabiola;
Norman, Jim C.;
Baldanzi, Gianluca;
Graziani, Andrea

Publication type:

Article

P-Rex1 Cooperates with PDGFRβ; to Drive Cellular Migration in 3D Microenvironments.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053982

By:

Campbell, Andrew D.;
Lawn, Samuel;
McGarry, Lynn C.;
Welch, Heidi C.;
Ozanne, Bradford W.;
Norman, Jim C.

Publication type:

Article

New Roles for Lysosomal Traffi cking in Morphogen Gradient Sensing.

Published in:

Science Signaling, 2011, v. 4, n. 171, p. 1, doi. 10.1126/scisignal.2002053

By:

Rainero, Elena;
Norman, Jim C.

Publication type:

Article

ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 30, p. 10352, doi. 10.1523/JNEUROSCI.1409-12.2012

By:

Eva, Richard;
Crisp, Sarah;
Marland, Jamie R. K.;
Norman, Jim C.;
Kanamarlapudi, Venkateswarlu;
ffrench-Constant, Charles;
Fawcett, James W.

Publication type:

Article

Genomic amplicons target vesicle recycling in breast cancer.

Published in:

2009

By:

Mills, Gordon B.;
Jurisica, Igor;
Yarden, Yosef;
Norman, Jim C.

Publication type:

journal article

Cancer cells with trapped nuclei cut their way through the extracellular matrix.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06351-6

By:

Dornier, Emmanuel;
Norman, Jim C.

Publication type:

Article

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02101-2

By:

Dornier, Emmanuel;
Rabas, Nicolas;
Mitchell, Louise;
Novo, David;
Dhayade, Sandeep;
Marco, Sergi;
Mackay, Gillian;
Sumpton, David;
Pallares, Maria;
Nixon, Colin;
Blyth, Karen;
Macpherson, Iain R.;
Rainero, Elena;
Norman, Jim C.

Publication type:

Article

Neuropilin-1/GIPC1 Signaling Regulates 51 Integrin Traffic and Function in Endothelial Cells.

Published in:

PLoS Biology, 2009, v. 7, n. 1, p. e1000025, doi. 10.1371/journal.pbio.1000025

By:

Valdembri, Donatella;
Caswell, Patrick T.;
Anderson, Kurt I.;
Schwarz, Juliane P.;
König, Ireen;
Astanina, Elena;
Caccavari, Francesca;
Norman, Jim C.;
Humphries, Martin J.;
Bussolino, Federico;
Serini, Guido

Publication type:

Article

Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72322-x

By:

Koessinger, Anna L.;
Koessinger, Dominik;
Stevenson, Katrina;
Cloix, Catherine;
Mitchell, Louise;
Nixon, Colin;
Gomez-Roman, Natividad;
Chalmers, Anthony J.;
Norman, Jim C.;
Tait, Stephen W. G.

Publication type:

Article

Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion.

Published in:

BioEssays, 2013, v. 35, n. 6, p. 523, doi. 10.1002/bies.201200160

By:

Rainero, Elena;
Norman, Jim C.

Publication type:

Article

Class I Rab11‐family interacting proteins are binding targets for the Rab14 GTPase.

Published in:

Biology of the Cell (Wiley-Blackwell), 2010, v. 102, n. 1, p. 51, doi. 10.1042/BC20090068

By:

Kelly, Eoin E.;
Horgan, Conor P.;
Adams, Christine;
Patzer, Tomasz M.;
Shúilleabháin, Deirdre M. Ní;
Norman, Jim C.;
McCaffrey, Mary W.

Publication type:

Article

Class I Rab11-family interacting proteins are binding targets for the Rab14 GTPase.

Published in:

Biology of the Cell (Wiley-Blackwell), 2009, v. 102, n. 1, p. 51

By:

Eoin E. Kelly;
Conor P. Horgan;
Christine Adams;
Tomasz M. Patzer;
Deirdre M. Ní Shúilleabháin;
Jim C. Norman;
Mary W. McCaffrey

Publication type:

Article

PKD1/PKCµ promotes avß3 integrin recycling and delivery to nascent focal adhesions.

Published in:

EMBO Journal, 2004, v. 23, n. 13, p. 2531, doi. 10.1038/sj.emboj.7600267

By:

Woods, Alison J.;
White, Dominic P.;
Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

Interaction of Paxillin with Poly(A)-Binding Protein 1 and Its Role in Focal Adhesion Turnover and Cell Migration.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 9, p. 3763, doi. 10.1128/MCB.25.9.3763-3773.2005

By:

Woods, Alison J.;
Kantidakis, Theodoros;
Sabe, Hisataka;
Critchley, David R.;
Norman, Jim C.

Publication type:

Article

B-Raf Acts via the ROCKII/LIMK/Cofilin Pathway To Maintain Actin Stress Fibers in Fibroblasts.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 13, p. 5937, doi. 10.1128/MCB.24.13.5937-5952.2004

By:

Pritchard, Catrin A.;
Hayes, Louise;
Wojnowski, Leszek;
Zimmer, Andreas;
Marais, Richard M.;
Norman, Jim C.

Publication type:

Article

Protein Kinase B/Akt Acts via Glycogen Synthase Kinase 3 To Regulate Recycling of αvβ3 and α5β1 Integrins.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 4, p. 1505, doi. 10.1128/MCB.24.4.1505-1515.2004

By:

Roberts, Marnie S.;
Woods, Alison J.;
Dale, Trevor C.;
van der Sluijs, Peter;
Norman, Jim C.

Publication type:

Article

MASTL promotes cell contractility and motility through kinase-independent signaling.

Published in:

Journal of Cell Biology, 2020, v. 219, n. 6, p. 1, doi. 10.1083/jcb.201906204

By:

Taskinen, Maria Emilia;
Narva, Elisa;
Conway, James R. W.;
Hinojosa, Laura Soto;
Lilla, Sergio;
Mai, Anja;
Franceschi, Nicola De;
Elo, Laura L.;
Grosse, Robert;
Zanivan, Sara;
Norman, Jim C.;
Ivaska, Johanna

Publication type:

Article

Tensin links energy metabolism to extracellular matrix assembly.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 4, p. 867, doi. 10.1083/jcb.201702025

By:

Dornier, Emmanuel;
Norman, Jim C.

Publication type:

Article

Photoactivation Approaches Reveal a Role for Rab11 in FGFR4 Recycling and Signalling.

Published in:

Traffic, 2014, v. 15, n. 6, p. 665, doi. 10.1111/tra.12168

By:

Haugsten, Ellen M.;
Brech, Andreas;
Liestøl, Knut;
Norman, Jim C.;
Wesche, Jørgen

Publication type:

Article

VEGFR1 (Flt1) Regulates Rab4 Recycling to Control Fibronectin Polymerization and Endothelial Vessel Branching.

Published in:

Traffic, 2009, v. 10, n. 6, p. 754, doi. 10.1111/j.1600-0854.2009.00898.x

By:

Jones, Matthew C.;
Caswell, Patrick T.;
Moran-Jones, Kim;
Roberts, Marnie;
Barry, Simon T.;
Gampel, Alexandra;
Mellor, Harry;
Norman, Jim C.

Publication type:

Article

Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 9, p. 4375, doi. 10.1093/nar/gkz214

By:

Linnane, Emily;
Davey, Paul;
Zhang, Pei;
Puri, Sanyogitta;
Edbrooke, Mark;
Chiarparin, Elisabetta;
Revenko, Alexey S;
Macleod, A Robert;
Norman, Jim C;
Ross, Sarah J

Publication type:

Article

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14646, doi. 10.1038/ncomms14646

By:

Gundry, Christine;
Marco, Sergi;
Rainero, Elena;
Miller, Bryan;
Dornier, Emmanuel;
Mitchell, Louise;
Caswell, Patrick T.;
Campbell, Andrew D.;
Hogeweg, Anna;
Sansom, Owen J.;
Morton, Jennifer P.;
Norman, Jim C.

Publication type:

Article

Integrins: masters and slaves of endocytic transport.

Published in:

Nature Reviews Molecular Cell Biology, 2009, v. 10, n. 12, p. 843, doi. 10.1038/nrm2799

By:

Caswell, Patrick T.;
Vadrevu, Suryakiran;
Norman, Jim C.

Publication type:

Article

Integrin Trafficking and the Control of Cell Migration.

Published in:

Traffic, 2006, v. 7, n. 1, p. 14, doi. 10.1111/j.1600-0854.2005.00362.x

By:

Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion.

Published in:

Carcinogenesis, 2008, v. 29, n. 3, p. 629

By:

Mirang Kim;
Hay-Ran Jang;
Jeong-Hwan Kim;
Seung-Moo Noh;
Kyu-Sang Song;
June-Sik Cho;
Hyun-Yong Jeong;
Jim C. Norman;
Patrick T. Caswell;
Gyeong Hoon Kang;
Seon-Young Kim;
Hyang-Sook Yoo;
Yong Sung Kim

Publication type:

Article

Endosomal integrin signals for survival.

Published in:

Nature Cell Biology, 2015, v. 17, n. 11, p. 1373, doi. 10.1038/ncb3261

By:

Rainero, Elena;
Norman, Jim C.

Publication type:

Article

Rab11 and Its Effector Rab Coupling Protein Contribute to the Trafficking of β1 Integrins during Axon Growth in Adult Dorsal Root Ganglion Neurons and PC12 Cells.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 35, p. 11654, doi. 10.1523/JNEUROSCI.2425-10.2010

By:

Eva, Richard;
Dassie, Elisa;
Caswell, Patrick T.;
Dick, Gunnar;
Ffrench-Constant, Charles;
Norman, Jim C.;
Fawcett, James W.

Publication type:

Article

FAK Acts as a Suppressor of RTK-MAP Kinase Signalling in <i>Drosophila melanogaster</i> Epithelia and Human Cancer Cells.

Published in:

PLoS Genetics, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pgen.1004262

By:

Macagno, Juan Pablo;
Diaz Vera, Jesica;
Yu, Yachuan;
MacPherson, Iain;
Sandilands, Emma;
Palmer, Ruth;
Norman, Jim C.;
Frame, Margaret;
Vidal, Marcos

Publication type:

Article