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- Title
The concept of translocational regulation.
- Authors
Hegde, Ramanujan S; Kang, Sang-Wook
- Abstract
Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocational regulation is proposed based on our current mechanistic understanding of ER protein translocation and general principles of regulatory control.
- Publication
The Journal of cell biology, 2008, Vol 182, Issue 2, p225
- ISSN
1540-8140
- Publication type
Journal Article
- DOI
10.1083/jcb.200804157