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- Title
Plasmid segregation: spatial awareness at the molecular level.
- Authors
Møller-Jensen, Jakob; Gerdes, Kenn
- Abstract
In bacteria, low-copy number plasmids ensure their stable inheritance by partition loci (par), which actively distribute plasmid replicates to each side of the cell division plane. Using time-lapse fluorescence microscopic tracking of segregating plasmid molecules, a new study provides novel insight into the workings of the par system from Escherichia coli plasmid R1. Despite its relative simplicity, the plasmid partition spindle shares characteristics with the mitotic machinery of eukaryotic cells.
- Publication
The Journal of cell biology, 2007, Vol 179, Issue 5, p813
- ISSN
1540-8140
- Publication type
Journal Article
- DOI
10.1083/jcb.200710192