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- Title
Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER.
- Authors
Titorenko, Vladimir I; Mullen, Robert T
- Abstract
Peroxisomes have long been viewed as semiautonomous, static, and homogenous organelles that exist outside the secretory and endocytic pathways of vesicular flow. However, growing evidence supports the view that peroxisomes actually constitute a dynamic endomembrane system that originates from the endoplasmic reticulum. This review highlights the various strategies used by evolutionarily diverse organisms for coordinating the flow of membrane-enclosed carriers through the peroxisomal endomembrane system and critically evaluates the dynamics and molecular mechanisms of this multistep process.
- Publication
The Journal of cell biology, 2006, Vol 174, Issue 1, p11
- ISSN
0021-9525
- Publication type
Journal Article
- DOI
10.1083/jcb.200604036