Title

Mathematical Modeling of a Flat-Membrane-Controlled Release Device.

Authors

RAMRAJ, RITESH; FARRELL, STEPHANIE; LONEY, NORMAN

Abstract

The closed form solution to a mathematical model of a flat membrane device successfully predicts the release profile of benzoic acid. Physically, the device consists of a given concentration of benzoic acid in octanol (reservoir) bounded by a microporous flat film (Cellgard 2400) with water-filled pores. The prediction shows excellent agreement with the experimentally derived release profile (maximum difference < 10%). Predicted results are obtained from the use of the steady state plus the first term of the transient solution (infinite series) and with the use of the first nonzero eigenvalue.

Subjects

MATHEMATICAL models; ARTIFICIAL membranes

Publication

Separation Science & Technology, 1999, Vol 34, Issue 11, p2251

ISSN

0149-6395

Publication type

Academic Journal

DOI

10.1081/SS-100100770