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- Title
Intermittent hirudin versus continuous heparin for anticoagulation in continuous renal replacement therapy.
- Authors
Hein, Ortrud Vargas; von Heymann, Christian; Diehl, Thorsten; Ziemer, Sabine; Ronco, Claudio; Morgera, Stanislao; Siebert, Gerda; Kox, Wofgang J; Neumayer, Hans H; Spies, Claudia
- Abstract
Besides possible bleeding complications a further problem in anticoagulation during continuous renal replacement therapy (CRRT) is the development of heparin-induced thrombocytopenia type II (HIT II) where further anticoagulation with heparin is contraindicated. The application of continuous hirudin as alternative for heparin caused bleeding complications by comparable filter efficacy. Aim of this prospective-controlled pilot study was to compare the efficacy and safety of intermittent hirudin and continuous heparin for anticoagulation during CRRT in critically ill patients.
- Publication
Renal failure, 2004, Vol 26, Issue 3, p297
- ISSN
0886-022X
- Publication type
Journal Article
- DOI
10.1081/jdi-120039529