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- Title
Low dose intravenous ascorbic acid for erythropoietin-hyporesponsive anemia in diabetic hemodialysis patients with iron overload.
- Authors
Lin, Chun-Liang; Hsu, Po-Yaur; Yang, Huan-Yu; Huang, Chiu-Ching
- Abstract
Recent report demonstrates that inadequate iron mobilization and defective iron utilization may cause recombinant erythropoieitin (rEPO) hyporesponsiveness in hemodialysis (HD) patients with iron overload. The effect of intravenous ascorbic acid (IVAA) in HD patients selected on the basis of iron overload and EPO resistance also has been proven. However, it is uncertain whether IVAA still works in diabetic ESRD patients with hyperferritinemia. Therefore, the aim of this study focusing on diabetic ESRD patients was to analyze the potential effect of low dose IVAA on improvement of anemia and erythropoiesis-related parameters when compared with control period.
- Publication
Renal failure, 2003, Vol 25, Issue 3, p445
- ISSN
0886-022X
- Publication type
Journal Article
- DOI
10.1081/jdi-120021157