Title

Hepatic cancer stem cells may arise from adult ductal progenitors.

Authors

Nikolaou, Kostas C; Talianidis, Iannis

Abstract

Cancer stem cells (CSCs) are defined as cells within tumors that can self-renew and differentiate into heterogeneous lineages of cancerous cells. The origin of CSCs is not well understood. Recent evidence suggests that CSCs in hepatocellular carcinoma could be generated via oncogenic transformation and partial differentiation of adult hepatic ductal progenitor cells.

Subjects

CANCER stem cells; PROGENITOR cells; THYMOCYTES; LIVER cancer; ONCOGENIC viruses

Publication

Molecular & Cellular Oncology, 2016, Vol 3, Issue 1, p1

ISSN

2372-3556

Publication type

Academic Journal

DOI

10.1080/23723556.2015.1021946