We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
ERK1/2 MAP kinases in cell survival and apoptosis.
- Authors
Lu, Zhimin; Xu, Shuichan
- Abstract
ERK1/2 is an important subfamily of mitogen-activated protein kinases that control a broad range of cellular activities and physiological processes. ERK1/2 can be activated transiently or persistently by MEK1/2 and upstream MAP3Ks in conjunction with regulation and involvement of scaffolding proteins and phosphatases. Activation of ERK1/2 generally promotes cell survival; but under certain conditions, ERK1/2 can have pro-apoptotic functions.
- Publication
IUBMB life, 2006, Vol 58, Issue 11, p621
- ISSN
1521-6543
- Publication type
Journal Article
- DOI
10.1080/15216540600957438