Title

Grevillosides R-S: glucosides of 5-alkylresorcinol derivatives from roots of Ardisia crispa (Thunb.) A. DC.

Authors

Long, Xing-xiang; Zhang, Shuang; Xiang, Li-juan; Hu, Rui-hang; Feng, Ting-ting; Zhou, Ying; Yin, Xin

Abstract

Grevillosides R-S (1–2), two new glucosides of 5-alkylresorcinol derivatives, were isolated from the roots of Ardisia crispa (Thunb.) A. DC. The structures of grevillosides R-S (1–2) were determined by 1D and 2D NMR, HR-MS, UV, IR experiments and by comparison of their spectroscopic and physical data with literature values. In this paper, grevillosides R-S (1–2) were tested for their radical-scavenging activity (DPPH and ABTS) and α-glucosidase inhibitory activity in vitro. Grevillosides R-S (1–2) exhibited weak DPPH radical-scavenging activity with IC50 values of 72.3 and 485.2 μM, respectively. Grevillosides R-S (1–2) exhibited no inhibitory activity against α-glucosidase.

Subjects

GLUCOSIDES; PRIMULACEAE; ANTIOXIDANTS; LITERATURE

Publication

Natural Product Research, 2025, Vol 39, Issue 1, p157

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786419.2023.2258545