Title

Antimicrobial triterpenes from Poulsenia armata miq. standl.

Authors

Rushdey El-Seedi †, Hesham

Abstract

Crude petroleum ether extract from the bark of Poulsenia armata showed antimicrobial activity. Activity-guided fractionation led to the isolation and structure elucidation of two active new triterpene derivatives, the stearate of glut-5-en-3β-ol ( 1 ) and 3β,28-diacetoxyurs-12-ene ( 4 ), for the first time as naturally occurring compounds. Compound 4 has previously been synthesized. The structures were determined by 1D- and 2D-NMR spectroscopy, mass spectrometry and chemical transformations. This is the first report on the chemistry and pharmacology of the genus.

Subjects

TERPENES; PETROLEUM; MASS spectrometry; NATURAL gas; OIL consumption; FOSSIL fuels

Publication

Natural Product Research, 2005, Vol 19, Issue 2, p197

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786410410001730724