Title

A new Pinoresinol-type lignan from Ligularia Kanaitizensis.

Authors

Li, Yun-Sen; Wang, Zheng-Tao; Zhang, Main; Luo, Shi-De; Chen, Ji-Jun

Abstract

A new pinoresinol-type Lignan, 9α-angloyloxypinoresinol ( 1 ), was isolated from the roots and rhizomes of Ligularia kanaitizensis (Franch.) Hand.-Mazz, in addition to a known compound, 9α -hydroxypinoresinol ( 2 ). The structure of this new lignan ( 1 ) was established on the basis of 1D and 2D NMR experiments. Anti-HIV-1 RT biological assay showed that 1 was inhibitory to HIV-1 RT.

Subjects

LIGNANS; BIOLOGICAL assay; AIDS; PHENYL compounds; SPECTRUM analysis; NATURAL products

Publication

Natural Product Research, 2005, Vol 19, Issue 2, p125

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786410410001704723