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- Title
Thrombin-dependent regulation of matrix metalloproteinase (MMP)-9 levels in human fetal membranes.
- Authors
Stephenson, Courtney D; Lockwood, Charles J; Ma, Yuehong; Guller, Seth
- Abstract
Amniochorion matrix metalloproteinase (MMP)-9 levels increase during labor, reaching a maximum in patients with preterm premature rupture of membranes (PPROM). Bleeding is a major risk factor for PPROM. Since such hemorrhage into the tissue factor-enriched decidua induces intense thrombin formation, we determined whether thrombin stimulates MMP levels in amniochorionic membranes.
- Publication
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2005, Vol 18, Issue 1, p17
- ISSN
1476-7058
- Publication type
Journal Article
- DOI
10.1080/14767050500123632