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- Title
Imatinib-responsive hypereosinophilia in a patient with B cell ALL.
- Authors
Robyn, Jamie; Noel, Pierre; Wlodarska, Iwona; Choksi, Mamta; O'neal, Patricia; Arthur, Diane; Dunbar, Cynthia; Nutman, Thomas; Klion, Amy
- Abstract
Hypereosinophilia is a rare presenting sign of acute lymphocytic leukemia. A 29-year-old male was diagnosed with idiopathic hypereosinophilic syndrome with respiratory symptoms. Although his peripheral blood eosinophilia decreased in response to treatment with imatinib mesylate, a follow-up bone marrow showed a diffuse infiltrate of myeloperoxidase-negative blasts. He was subsequently diagnosed with CD10 positive precursor B lymphoblastic leukemia. This case underscores the importance of follow-up bone marrow examination in patients who demonstrate imatinib mesylate-responsive eosinophilia.
- Publication
Leukemia & lymphoma, 2004, Vol 45, Issue 12, p2497
- ISSN
1042-8194
- Publication type
Journal Article
- DOI
10.1080/10428190400005288