Title

Perangustols A and B, a pair of new azaphilone epimers from a marine sediment-derived fungus Cladosporium perangustm FS62.

Authors

Fan, Zhen; Sun, Zhang-Hua; Liu, Hong-Xin; Chen, Yu-Chan; Li, Hao-Hua; Zhang, Wei-Min

Abstract

A pair of new azaphilone epimers, perangustols A-B (1–2), and two new natural products (3–4), together with two known metabolites (5–6) were isolated from the culture of the marine sediment-derived fungusCladosporium perangustumFS62. The structures of these compounds were established on the basis of extensive spectroscopic analysis. The isolated compounds (1–6) were evaluated for their cytotoxic activities against the SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. Nonetheless, no significant activity was observed.

Publication

Journal of Asian Natural Products Research, 2016, Vol 18, Issue 11, p1024

ISSN

1028-6020

Publication type

Academic Journal

DOI

10.1080/10286020.2016.1181623