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- Title
A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.
- Authors
Yang, De-Lan; Mei, Wen-Li; Zeng, Yan-Bo; Guo, Zhi-Kai; Wei, Dai-Jing; Liu, Shou-Bai; Wang, Qing-Huang; Dai, Hao-Fu
- Abstract
A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C was elucidated by spectroscopic techniques (UV, IR, 1D, and 2D NMR) and HR-ESI-MS analyses. These compounds exhibited antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees.
- Publication
Journal of Asian natural products research, 2013, Vol 15, Issue 3, p315
- ISSN
1477-2213
- Publication type
Journal Article
- DOI
10.1080/10286020.2012.762641