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- Title
A new ganoderic acid from Ganoderma lucidum mycelia.
- Authors
Wang, Jia-Le; Li, Ying-Bo; Liu, Ru-Ming; Zhong, Jian-Jiang
- Abstract
A new ganoderic acid (GA), 7-O-ethyl ganoderic acid O (GA-O) (1), together with two known compounds, GA-T (2) and GA-Me (3), was isolated and purified from fermented mycelia of Ganoderma lucidum. The structure of the new triterpenoid was elucidated on the basis of the interpretation of extensive spectroscopic data (HR-MS, IR, UV, 1D and 2D NMR) as 3 alpha,15 alpha,22-triacetoxy-7 alpha-ethoxy-5 alpha-lanost-8,24E-dien-26-oic acid. The new compound was found to contain a rare ethoxyl group at C-7. In addition, its cytotoxicity against 95D and HeLa human cancer cell lines was also evaluated.
- Publication
Journal of Asian natural products research, 2010, Vol 12, Issue 8, p727
- ISSN
1477-2213
- Publication type
Journal Article
- DOI
10.1080/10286020.2010.493506