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- Title
Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia.
- Authors
Hudson, Craig; Hudson, Susan Patricia; Hecht, Tracy; MacKenzie, Joan
- Abstract
Intact protein rich in tryptophan was not seen as an alternative to pharmaceutical grade tryptophan since protein also contains large neutral amino acids (LNAAs) that compete for transport sites across the blood-brain barrier (BBB). Deoiled gourd seed (an extremely rich source of tryptophan-22 mg tryptophan/1 g protein) was combined with glucose, a carbohydrate that reduces serum levels of competing LNAAs which was then compared to pharmaceutical grade tryptophan with carbohydrate as well as carbohydrate alone.
- Publication
Nutritional neuroscience, 2005, Vol 8, Issue 2, p121
- ISSN
1028-415X
- Publication type
Journal Article
- DOI
10.1080/10284150500069561