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- Title
Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.
- Authors
Ong, Ken K; Loos, Ruth J F
- Abstract
In a systematic review, we identified 21 separate studies with data on the association between rapid infancy weight gain, up to age 2 y, and subsequent obesity risk. Uniformly all studies reported significant positive associations. We transformed the reported effect sizes to a standard infancy weight gain exposure, and found that further differences in study design accounted for much of the variation in risk. An accompanying paper by Melinda Yeung reminds us that there are benefits of postnatal catch-up growth in certain populations, and suggests that genetic and nutritional factors could moderate the unhealthy translation of rapid infancy weight gain to visceral fat and insulin resistance. Further evidence is needed, and we will need to rigorously test the benefits and risks of any interventions. However, the concept of "healthy" rapid catch-up infancy growth is an attractive prospect.
- Publication
Acta paediatrica (Oslo, Norway : 1992), 2006, Vol 95, Issue 8, p904
- ISSN
0803-5253
- Publication type
Journal Article
- DOI
10.1080/08035250600719754