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- Title
High efficacy of pre-operative trastuzumab combined with paclitaxel following doxorubicin & cyclophosphamide in operable breast cancer.
- Authors
Paluch-Shimon, Shani; Wolf, Ido; Goldberg, Hadassah; Evron, Ella; Papa, Moshe Z; Shabtai, Moshe; Barsuk, Daphna; Yosepovich, Ady; Modiano, Tami; Catane, Raphael; Kaufman, Bella
- Abstract
Trastuzumab in combination with adjuvant chemotherapy improves disease free survival and overall survival in HER2 over-expressing breast cancer patients. Data concerning the use of trastuzumab in the neo-adjuvant setting is limited. We aimed to compare outcome of HER2 over-expressing breast cancer patients treated with either standard chemotherapy, consisting of doxorubicin, cyclophosphamide and a taxane to outcome of patients treated with the same chemotherapy regimen with the addition of trastuzumab in concurrence with paclitaxel.
- Publication
Acta oncologica (Stockholm, Sweden), 2008, Vol 47, Issue 8, p1564
- ISSN
1651-226X
- Publication type
Journal Article
- DOI
10.1080/02841860802060844