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- Title
The value of TOP2A gene copy number variation as a biomarker in breast cancer: Update of DBCG trial 89D.
- Authors
Nielsen, Kirsten Vang; Ejlertsen, Bent; Møller, Susanne; Jørgensen, Jan Trøst; Knoop, Ann; Knudsen, Helle; Mouridsen, Henning T
- Abstract
Previous analyses of TOP2A and HER2 in the Danish Breast Cancer Coopererative Group (DBCG) trial 89D suggested that TOP2A amplifications and possible also deletions are predictive markers for the effect of adjuvant epirubicin in patients with primary breast cancer. We present an updated and extended statistical analysis, requested for IVD-labeling of TOP2A testing.
- Publication
Acta oncologica (Stockholm, Sweden), 2008, Vol 47, Issue 4, p725
- ISSN
1651-226X
- Publication type
Journal Article
- DOI
10.1080/02841860801995396