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- Title
Trends in the use of androgen deprivation in prostate cancer.
- Authors
Salminen, Eeva K; Wickström, Jan-Erik; Vahlberg, Tero; Duchesne, Gillian M
- Abstract
The aim of this study was to assess current management of prostate cancer patients with elevated prostate-specific antigen (PSA) among Finnish urologists and oncologists. Four case scenarios were presented: postprostatectomy PSA relapse, postradiotherapy (RT) relapse with a slowly or rapidly rising PSA, elderly patients prior to treatment. Management preferences and the use of androgen deprivation (AD) in prostate cancer were surveyed. Eighty-two informative replies, 60 from 90 practicing urologists (67%) and 22 from 70 practicing oncologists (31%) were received. For postprostatectomy relapse, salvage RT or follow-up until significant rise of PSA were the favored recommendations. For post RT with slowly or rapidly rising PSA and treatment of non-radical cases an active approach with even small PSA rises and immediate androgen deprivation were favored. For intervention, the recommended PSA border values ranged from 0.5 to > 100 ng/mL. More research is needed focusing on criteria and timing of AD in the treatment of prostate cancer.
- Publication
Acta oncologica (Stockholm, Sweden), 2004, Vol 43, Issue 4, p382
- ISSN
0284-186X
- Publication type
Journal Article
- DOI
10.1080/02841860410029500